HArmonyCA™

$449.00

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Product details

Manufacturer:
Allergan
Active Substance(s):
HYALURONIC ACID, CALCIUM HYDROXYAPATITE, LIDOCAINE
Strength:
20mg/ml, 55.7%, 0.3%
Pack size:
2 x 125ml

Product description

HArmonyCa™ is the first hybrid tissue biostimulator designed to restore natural skin radiance and reduce signs of aging. Its unique combination of two active ingredients – cross-linked hyaluronic acid and calcium hydroxyapatite enclosed in microspheres – allows for long-lasting results that are visible after just one treatment session. The cross-linked hyaluronic acid immediately increases tissue volume and provides a lifting effect, while the calcium hydroxyapatite is known for its long-lasting action. Its microspheres stimulate fibroblasts to grow and produce extracellular matrix components such as collagen and elastin. HArmonyCa™ is applied deep into the dermis to add volume and instantly lift the skin. At the same time, the calcium hydroxyapatite microspheres start to stimulate fibroblasts, resulting in increased production of collagen type I and III and elastin. As the hyaluronic acid is biodegraded, a stable collagen framework is formed in its place – similar to the natural process of skin renewal. What can you expect from HArmonyCa™? First and foremost, a treatment with this product provides an immediate increase in tissue volume, smoothing and firming of the skin, and reduction of wrinkles in the treated area. The full effects of the therapy are visible between 3 and 4 months after the treatment, when the stable collagen framework is formed. Calcium hydroxyapatite has stimulating properties that last up to 12 months after the product is administered, and the results of the treatment can be visible for up to 3 years. Another advantage of HarmonyCa™ is the recommended treatment series – only one treatment is needed to enjoy long-lasting effects for many months. The microspheres of calcium hydroxyapatite have a diameter of 25 to 45 microns (55.7%), cross-linked sodium hyaluronate gel (20 mg/ml), phosphate buffer, and lidocaine hydrochloride (3 mg/ml).

Tier

Packs Discount (%) For Each
1 - 5 $449.00
6 - 10 0.45 % $447.00
11 - 20 0.89 % $445.00
21+ 1.11 % $444.00

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FAQ

HArmonyCA™ is a hybrid injectable dermal filler that uniquely combines hyaluronic acid (HA) with calcium hydroxyapatite (CaHA) to address volume loss and stimulate collagen production. Developed by Allergan Aesthetics, this dual-effect formulation is designed to provide both immediate volumizing effects and long-lasting skin firmness through endogenous collagen stimulation. The product is indicated for facial soft tissue augmentation, particularly targeting the cheeks, jawline, and chin, where structural support often diminishes with age.

Patients in clinical trials reported high satisfaction, with 91.6% noting an improvement in treated areas and a 4.1/5 satisfaction score. Visible lifting effects can last up to 12 months, and collagen-stimulating benefits may persist for up to 3 years, depending on individual response.

HArmonyCA™ should be administered into the deep dermal or sub-dermal layers by trained professionals. The inclusion of lidocaine reduces pain during the procedure.

  • Injection depth: Deep dermal to sub-dermal
  • Treatment areas: Cheeks, jawline, chin
  • Session volume: Clinical trials used approx. 7.4 mL for full-face treatment
  • Pain management: Contains lidocaine for patient comfort
  • Results onset: Immediate lifting + long-term improvement over months 

HArmonyCA™ is indicated for:

  • Facial volume loss correction
  • Structural support restoration
  • Skin architecture enhancement

Contraindications include:

  • Allergy to any component, including lidocaine
  • Active skin infections or inflammatory conditions
  • Autoimmune disorders affecting the skin

Common side effects:

  • Erythema
  • Edema
  • Pain and tenderness
  • Itching at the injection site

These reactions are typically mild and resolve within 24–48 hours, with swelling subsiding in up to 7 days.

The hybrid filler is composed of:

  • Hyaluronic acid (HA): For immediate volume and hydration
  • Calcium hydroxyapatite (CaHA): For long-term collagen stimulation
  • Lidocaine: A local anesthetic to minimize injection discomfort 

Each HArmonyCA™ package includes:

  • 6 syringes totaling 7.5 mL of injectable gel
  • Individual sterile packaging per syringe
  • Accompanying product documentation for administration 

Yes, like all dermal fillers, it may cause mild, temporary side effects, including:

  • Redness
  • Swelling
  • Tenderness
  • Bruising or itching
  • Rarely, nodules or palpable material, which may require massage

Side effects are generally short-lived, resolving in a few days to a week.

To ensure product integrity:

  • Store between 2°C to 25°C (36°F to 77°F)
  • Protect from direct sunlight and freezing
  • Keep in original packaging until use
  • Do not reuse syringes or leftover product

For best results, always follow storage and usage instructions provided by the manufacturer or healthcare provider.

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