INTRALINE® ONE

INTRALINE® ONE is a biphasic hyaluronic acid (HA) dermal filler designed for subtle correction and definition in delicate areas of the face. With a medium gel sphere size and a HA concentration of 20 mg/mL, it provides controlled, natural-looking enhancement for tear troughs, smoker’s lines, cupid’s bow, nasolabial folds, and crow’s feet. This filler offers both structure and flexibility due to its BDDE cross-linked HA suspended in non-cross-linked HA, enabling it to resist deformation while remaining easy to inject. INTRALINE® ONE delivers moderate lift and smooth contouring, making it ideal for initial treatments or patients seeking a refined, natural appearance.

• HA Type: Biphasic (cross-linked + carrier gel)
• Primary Use: Tear trough correction, perioral lines, fine lines
• Result Longevity: Typically 6–12 months
• Target Layer: Mid dermis for optimal integration

INTRALINE® ONE is injected into the mid-dermal layer using 27G Terumo needles, offering precision for fine lines and shallow folds. It is prefilled and ready-to-use, ensuring consistent results.

• Level of Injection: Mid dermis
• Technique: Linear threading or micro-papular injection
• HA Concentration: 20 mg/mL
• Needles Included: 2 x 27G Terumo
• Volume per Syringe: 1.0 mL
• Consistency: Medium gel sphere size for balanced lift and mobility

INTRALINE® ONE is indicated for patients seeking treatment of mild to moderate facial wrinkles and subtle enhancements, particularly in thin or delicate skin areas.

Indications:

• Tear trough (under-eye hollowing)
• Perioral “smoker’s lines”
• Cupid’s bow and lip border definition
• Crow’s feet and forehead lines
• Nasolabial folds and marionette lines

Contraindications:

• Hypersensitivity to hyaluronic acid or BDDE
• Active skin infections or inflammation
• Autoimmune disorders or coagulation issues
• Pregnancy or breastfeeding

Side Effects:

• Common: Swelling, redness, tenderness, or bruising at the injection site
• Less Common: Temporary unevenness or nodules
• Rare: Allergic reaction, granuloma, vascular occlusion

INTRALINE® ONE consists of 20 mg/mL non-animal hyaluronic acid, cross-linked using BDDE, suspended in a non-cross-linked HA carrier to facilitate easy flow and even distribution.

• HA Source: Non-animal origin, bio-fermentation
• HA Concentration: 20 mg/mL
• Gel Structure: Biphasic (cross-linked spheres + carrier HA)
• Crosslinking Agent: BDDE (<1 µg/mL)
• Particle Size: Medium (suitable for soft tissue blending)

The product is supplied in a sterile blister pack, ready for single-patient use. Each package contains a syringe and accessories necessary for standard filler procedures.

• Package Includes:
  • 1 x 1.0 mL prefilled syringe
  • 2 x 27G Terumo needles
• Sterility: Moist heat or validated EO sterilized
• Packaging: CE-certified, tamper-proof blister pack

This filler is generally safe and well tolerated, though like all injectable products, localized side effects can occur and typically resolve within a few days.

• Mild Effects: Redness, swelling, tenderness, or bruising (3–7 days)
• Moderate Effects: Temporary unevenness, sensitivity, or itching
• Severe (rare): Hypersensitivity, granuloma, infection, vascular events

Proper storage conditions are essential to preserve product stability and ensure sterility until use.

• Storage Temperature: 2–25°C
• Avoid: Freezing, direct sunlight, excessive humidity
• Shelf Life: 2–3 years from the manufacturing date (unopened)
• Use Note: Do not reuse. Discard any unused material after opening