CROMA POLYPHIL™ EYE

CROMA PhilArt EYE is an innovative intradermal biorevitalizing injectable designed specifically for the periorbital area, including eye contours, eyebrows, and other delicate skin zones. It is based on PN-HPT® (Polynucleotides Highly Purified Technology), which stimulates fibroblast activity, promotes collagen synthesis, and improves skin elasticity and hydration without causing significant edema or tissue pull. This low-concentration (15 mg/2 ml) formulation is ideal for treating thin, sensitive skin prone to wrinkles, sagging, or signs of fatigue. PhilArt EYE is commonly used both as a standalone treatment and as a primer before other aesthetic procedures such as laser, fillers, or surgery. It is clinically proven to reduce fine lines, superficial wrinkles, and give the eye area a more refreshed, youthful appearance.

PhilArt EYE is administered via intradermal injection using the serial puncture or linear retrograde technique.

Key Features:

• Specifically formulated for periocular and delicate areas
  
• Uses PN-HPT® to activate skin regeneration without swelling
  

Protocol:

• Volume per session: 1–2 ml
  
• Frequency: One session every 14–21 days
  
• Total sessions: 3–4
  
• Technique: Serial puncture or linear retrograde injections spaced 0.5–1 cm
  
• Needle size: 30G ½ (13 mm) 

Indications:

• Revitalization of tired eyes
  
• Improvement of fine lines and crow’s feet
  
• Eyebrow ptosis
  
• Use in younger patients for prevention and in mature skin for visible rejuvenation
  
• Skin priming before aesthetic procedures (laser, filler, RF, peeling)
  

Contraindications:

• Hypersensitivity to any component
  
• Infection or inflammation at the injection site
  
• Pregnancy or breastfeeding
  

Possible Side Effects:

• Localized redness, swelling, or bruising
  
• No severe adverse events reported in clinical evaluations 

Each syringe contains:

• 15 mg of PN-HPT® (Highly Purified Polynucleotides) in 2 ml solution
  
• Sterile, preservative-free formulation for intradermal use 

Package Contents:

• 1 × 2 ml pre-filled syringe
  
• 2 × 30G ½ needles (13 mm)
  
• Individually boxed with sterile, single-use components 

PhilArt EYE is generally very well tolerated.

Reported Side Effects:

• Mild local reactions: swelling, bruising, erythema at injection site
  
• No significant side effects or long-term complications observed
  
• Patients should be informed of potential minimal risks related to intradermal procedures 

Storage Conditions:

• Store at 2–25°C
  
• Do not freeze
  
• Protect from light and contamination
  
• Use only within the expiry date
  
• Keep in original sterile packaging until use