RENEFIL ULTRA PLUS

RENEFIL ULTRA PLUS is a high-viscosity cross-linked hyaluronic acid (HA) dermal filler enriched with polynucleotides (PN) and 0.3% lidocaine, specifically formulated for deep volumization and structural facial contouring. It is ideal for restoring volume in the cheeks, chin, jawline, and nasolabial folds, as well as for non-surgical rhinoplasty. Thanks to its high elasticity and cohesiveness, RENEFIL ULTRA PLUS provides maximum projection, long-lasting lift, and strong tissue support, while PN enhances skin regeneration and hydration. This combination ensures both instant volumizing effects and long-term dermal remodeling.

• Indicated for: Deep volume restoration and facial contouring
• Texture: Dense, elastic, and highly durable
• Clinical duration: Up to 14–18 months
• Comfort: Contains lidocaine for reduced injection discomfort

RENEFIL ULTRA PLUS is injected into the deep dermis or subcutaneous/supraperiosteal layers using a 25G or 27G needle or cannula, depending on the treatment zone. Its dense texture allows for precise contouring and projection in areas requiring strong lift and structure.

• Injection depth: Deep dermis, subcutaneous, or supraperiosteal
• Needle or cannula size: Typically 25G or 27G
• Injection techniques: Bolus, retrograde linear, fanning, or tower technique
• Treatment areas: Cheeks, chin, jawline, zygoma, nasal bridge
• Contains lidocaine: 0.3% for reduced pain
• Visible effects: Immediate, with structural stability and progressive improvement

RENEFIL ULTRA PLUS is indicated for patients requiring robust volume enhancement, facial sculpting, and deep wrinkle correction. It is best suited for advanced aesthetic indications.

Indications:

• Midface volume loss
• Chin augmentation and projection
• Jawline contouring
• Nasolabial fold correction
• Non-surgical rhinoplasty
• Temple filling

Contraindications:

• Allergy to HA, lidocaine, or PN
• Pregnancy or lactation
• Active skin inflammation or infection
• Autoimmune or connective tissue disease
• Coagulation disorders or recent anticoagulant therapy

Side Effects:

• Redness, swelling, bruising, or pain at injection site
• Lumpiness or firmness
• Rare: Vascular occlusion, nodules, or delayed hypersensitivity

RENEFIL ULTRA PLUS combines a high concentration of cross-linked hyaluronic acid with polynucleotides and lidocaine, offering both structural and regenerative benefits.

• Hyaluronic Acid (HA): 20 mg/mL
• Polynucleotides (PN): 1.875 mg/mL
• Lidocaine Hydrochloride: 0.3% (3 mg/mL)
• Form: Viscoelastic, sterile, non-pyrogenic gel
• pH: Physiologically balanced for skin compatibility

The product is delivered in a ready-to-use, prefilled syringe format with accessories for safe and efficient injection.

• 1 prefilled syringe with 1 mL of RENEFIL ULTRA PLUS
• 2 sterile needles or cannulas (typically 25G or 27G)
• Traceability labels for medical documentation
• Sterile blister packaging
• Instructions for use and safety information

RENEFIL ULTRA PLUS is generally safe when injected correctly by trained professionals. Side effects are usually localized and short-term.

Common Side Effects:

• Mild to moderate bruising, edema, or pain
• Erythema or firmness at the injection area

Rare Adverse Events:

• Lumps or granulomas
• Skin discoloration
• Infection or abscess
• Vascular compromise (requires immediate intervention)

Proper storage maintains the sterility and effectiveness of RENEFIL ULTRA PLUS. Follow these guidelines to preserve product integrity.

• Storage temperature: 2°C to 25°C (36°F to 77°F)
• Keep away from direct sunlight
• Do not freeze
• Use immediately after opening
• Do not resterilize or reuse – single-use only