RENEFIL DEEP PLUS

RENEFIL DEEP PLUS is a next-generation hybrid dermal filler that combines cross-linked hyaluronic acid (HA) with polynucleotides (PN) and lidocaine to provide both volumizing and skin-regenerative benefits. Designed for deep dermal injection, it effectively corrects moderate to severe wrinkles, including nasolabial folds, marionette lines, and mid-face volume loss, while also improving skin tone, hydration, and elasticity. The formulation delivers high viscosity and elasticity for better tissue support and long-lasting outcomes, with added PN enhancing collagen production, skin texture, and hydration. This filler also contains 0.3% lidocaine for improved patient comfort during the procedure.

• Type: HA + PN + Lidocaine hybrid filler
• Target areas: Mid-face, nasolabial folds, marionette lines, chin, cheeks
• Texture: High viscosity, excellent moldability
• Clinical duration: Up to 12–14 months

RENEFIL DEEP PLUS is administered via deep dermal or subcutaneous injection using a 27G or 30G needle, depending on the application area. Its rheological profile allows for stable volume restoration with low injection force.

• Injection depth: Deep dermis or subcutaneous layer
• Needle size: 27G or 30G (typically supplied with 2 needles per syringe)
• Target areas: Cheeks, nasolabial folds, chin, marionette lines
• Injection techniques: Linear threading, bolus, fanning
• Pain control: Contains 0.3% lidocaine for patient comfort
• Session time: Typically 20–30 minutes
• Results visible: Immediately, with improvement over 1–2 weeks

RENEFIL DEEP PLUS is indicated for moderate to severe facial volume loss, deep wrinkles, and midface contouring. Its combination of HA and PN makes it especially suitable for patients seeking volumization and skin rejuvenation in a single product.

Indications:

• Nasolabial folds
• Marionette lines
• Midface volume loss
• Chin augmentation
• Zygomatic enhancement

Contraindications:

• Hypersensitivity to HA, PN, or lidocaine
• Pregnancy or breastfeeding
• Active infection or inflammation at the treatment site
• Autoimmune disorders
• Bleeding or coagulation abnormalities

Side Effects:

• Mild bruising, swelling, or redness at the injection site
• Tenderness or itching
• Rare: Nodules, allergic reaction, or vascular occlusion

RENEFIL DEEP PLUS features a scientifically optimized formulation for safety, performance, and skin-enhancing results.

• Cross-linked Hyaluronic Acid (HA): 20 mg/mL
• Sodium Polynucleotide (PN): 1.875 mg/mL
• Lidocaine HCl: 0.3% (3 mg/mL)
• pH-balanced, clear viscoelastic gel
• Sterile, non-pyrogenic

Each RENEFIL DEEP PLUS package includes a prefilled syringe and accessories for immediate use. The product is CE-certified and manufactured under ISO 13485 standards.

• 1 prefilled syringe with 1 mL of RENEFIL DEEP PLUS
• 2 sterile needles (typically 27G or 30G)
• Patient tracking labels
• Instructions for use
• Individually boxed and sterile-packaged

RENEFIL DEEP PLUS is generally well-tolerated with a low incidence of side effects. Reactions are usually mild and transient.

Common Side Effects:

• Erythema, edema, or bruising
• Pain, itching, or tenderness

Rare Adverse Effects:

• Inflammatory nodules
• Infection at injection site
• Vascular compromise (if injected intravascularly)
• Hypersensitivity reaction (due to lidocaine or PN)

Proper storage is essential to maintain the sterility and rheological properties of the product.

• Storage temperature: 2°C to 25°C (36°F to 77°F)
• Keep away from light and heat
• Do not freeze
• Store in original sealed packaging
• Single-use only – do not resterilize or reuse